Stats by Source
Total, split by cell line (COSMIC CL / DepMap / PubMed) vs tissue (COSMIC primary tissue)
Total = all mutations for this gene across every source.
Cell line = COSMIC Cell Lines Project + DepMap + PubMed.
Tissue = COSMIC primary-tissue (patient tumour) samples.
Total can exceed cell line + tissue: COSMIC tissue-derived models sit only in global, and a peptide can be shared across both.
| Total | Cell line | Tissue | |
|---|---|---|---|
| Mutations | 50 | 39 | 0 |
| Samples | 43 | 39 | 0 |
| Peptides | 44 | 35 | 0 |
Function
ODAD1 · Outer dynein arm docking complex subunit 1
This gene encodes a coiled-coil domain-containing protein that is a component of the outer dynein arm docking complex in cilia cells. Mutations in this gene may cause primary ciliary dyskinesia 20. [provided by RefSeq, May 2013].
Isoforms & Proteins
2 transcripts · UniProt mapping is sequence-verified (AA-safe)
Each Ensembl transcript (ENST) this gene is mutated on, with its matched UniProt accession.
The mapping is sequence-verified: the UniProt sequence is identical to the transcript translation, so amino-acid positions line up exactly. A * marks an unreviewed (TrEMBL) entry.
Counts are mutations and unique mutant peptides on each transcript.
| Transcript | UniProt | Mutations | Peptides |
|---|---|---|---|
| ENST00000674294 | A0A6I8PTZ2* | 39 | 35 |
| ENST00000315396 | Q96M63 | 11 | 11 |
Gene Properties
Recurrent Mutations
All 11 amino-acid changes on canonical ENST00000315396 · needle height = samples · drag the mini-map to zoom
A lollipop / needle plot – the standard way to show recurrent mutations along a protein (as used by cBioPortal and MutationMapper).
X-axis = amino-acid position in the protein.
Needle height & head size = how often that exact amino-acid change was observed (its recurrence). Tall/large heads are mutational hotspots.
The most recurrent changes are labelled; hover any needle for the change, position and counts.
Mutation frequency across cancer types
% of samples with a missense/complex mutation in ODAD1 · cell line vs tissue
For each cancer type, the fraction of samples that carry at least one missense/complex mutation anywhere in ODAD1 – counted as distinct samples (a sample counts once no matter how many mutations it has).
Split into cell line and tissue; each cell shows mutated / total and the percentage. Cohorts with <20 samples are omitted. Ordered by combined frequency.
| Cancer type | Cell lines | Tissue samples |
|---|---|---|
| T-Lymphoblastic Leukemia | 5/40 12% | 0/0 0% |
| T-Cell Non-Hodgkins Lymphoma | 1/26 4% | 0/0 0% |
| Oral Cavity Carcinoma | 1/54 2% | 0/0 0% |
| Osteosarcoma | 1/45 2% | 0/166 0% |
| Endometrial Carcinoma | 2/42 5% | 1/612 0% |
| Ewings Sarcoma | 1/63 2% | 0/262 0% |
| Non-Small Cell Lung Carcinoma | 3/304 1% | 1/1390 0% |
| Cervical Carcinoma | 0/35 0% | 1/422 0% |
| Non-Cancerous | 2/104 2% | 0/830 0% |
| Colorectal Carcinoma | 4/143 3% | 1/3239 0% |
| Neuroendocrine Tumour | 1/154 1% | 0/577 0% |
| Melanoma | 3/210 1% | 0/1899 0% |
| Other Sarcomas | 1/69 1% | 0/699 0% |
| Squamous Cell Lung Carcinoma | 1/57 2% | 0/810 0% |
| Bladder Carcinoma | 1/58 2% | 0/956 0% |
| Ovarian Carcinoma | 1/109 1% | 0/998 0% |
| Breast Carcinoma | 3/144 2% | 0/3264 0% |
| Glioma | 2/52 4% | 0/2127 0% |
| Esophageal Squamous Cell Carcinoma | 2/51 4% | 0/2550 0% |
| Prostate Carcinoma | 1/13 8% | 0/2105 0% |
| B-Lymphoblastic Leukemia | 1/55 2% | 0/2640 0% |
| Other Blood Cancers | 1/61 2% | 0/2725 0% |
| Hepatocellular Carcinoma | 1/46 2% | 0/2210 0% |
Mutation Distribution
Where ODAD1 is mutated · all tissues, split by cell line vs tissue
How many mutations in ODAD1 were found in each tissue, across the whole database.
Each bar is a tissue (cell-line and tissue names are merged to the standard tissue), split into cell line and tissue (patient tumour) contributions.
This shows the cancer-context where this gene is recurrently altered.
Mutations
All 50 mutations in ODAD1
Every mutation record for this gene, across all samples and sources.
The Sample column links to the cell line (cell-line samples) or the tissue type (tissue samples).
Use the Type / Source filters, the search box, and column sorting to explore; each CAN-IMMUNE ID opens the full mutation & peptide view.
| ID | Sample | Transcript | AA Change | CDS | Type | Source | Mutant Peptide | Wild-type Peptide |
|---|